Common features of toons

An exaggerated, usually anthropomorphic appearance based on some realistic animal or object
A grossly caricatured appearance, if human (South Park)
An innate sense of comedic timing (Bonkers)
Being put into funny situations if ostensibly unfunny (i.e., deadpan characters such as Droopy Dog)
An intense focus on a single-minded goal, such as hunting (Elmer Fudd), catching prey (Sylvester the cat, Wiley E. Coyote, Humphrey the Bear), or capturing the object of one's romantic feelings (Pepé Le Pew, Johnny Bravo), generally with comedic results.
A usual disregard for the physical laws that govern our Universe (and a reciprocal disregard of those laws for them)